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 The project was carried out from 2012 to 2013 in three northern mountainous provinces, namely Lang Son, Bac Kan, and Son La. It was an integrated research work characterized by utilizing several diagnostic methods, including epidemiologic survey, clinical observations, ELIZA, blood smear, and laboratory animal incubation. Results showed that the prevalence of the disease on the buffalo herds of the studied areas ranged from 11.25% to 14.17%. Buffaloes infected with T. evansi often manifested some main clinical symptoms such as thin body condition, prolonged diarrhea, conjunctivitis, and cornea.

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 In addition, changes of hematological parameters in the T.evansi infected buffaloes i.e. the decreases in hemoglobin concentration, blood volume ratio, hemoglobin, hemoglobin concentration, and serum protein content were found. Moreover, it was shown that drugs such as azidin and trypamydium were safe and effective against T.evansi in buffaloes. Also, the proposed treatment regimens with the components of antiprotozoal drugs and preventive measures such as the eradication of the pathogen on the host, anti- insect vector trypanosomiasis, and the prevention of T.evansi reinfection revealed high efficiency with cure rate of 100% and 12% decrease in the prevalence of the disease in experimental buffalo populations.

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The research results are expected to test on other animals around T.evansi infected buffaloes and widely replicated in the studied areas and other northern mountainous provinces in Vietnam.